CD279 (PD-1) Mouse anti-Human, FITC, Clone: MIH4, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-9969-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15556656

Quantity Price
1 £ 142.93 / 100 tests
EU Stock 2
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Description and Specification

Specification

Conjugate FITC
Quantity 100 tests
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Clone MIH4
Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Applications Flow Cytometry
Regulatory Status RUO
Species Reactivity Human
Concentration 5μL (2.0μg)/test
Antigen CD279 (PD-1)
Isotype IgG1
Primary or Secondary Primary

The MIH4 monoclonal antibody reacts with the human PD-1 (programmed death-1), a 55kDa member of the immunoglobulin superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease. PD-1 is expressed predominantly on activated T and B lymphocytes. Two novel members of the B7 family have been identified as the PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. The MIH4 antibody recognizes a different epitope than antibody clones J105.