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CD279 (PD-1), FITC, clone: MIH4, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-9969-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15546656

  • £61.11 / 25 tests


EU Stock 4
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Description

Description

Description: The MIH4 monoclonal antibody reacts with the human PD-1 (programmed death-1), a 55kDa member of the immunoglobulin superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease. PD-1 is expressed predominantly on activated T and B lymphocytes. Two novel members of the B7 family have been identified as the PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. The MIH4 antibody recognizes a different epitope than antibody clones J105.Applications Reported: This MIH4 antibody has been reported for use in flow cytometric analysis.Applications Tested: This MIH4 antibody has been pre-titrated and tested by flow cytometric analysis of PHA-stimulated normal human peripheral blood cells. This can be used at 5 μL (2.0 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD279 (PD-1)
Monoclonal
5μl/Test
PBS with 0.2% BSA, 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q15116
PD1
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
MIH4
FITC
PDCD1
Conjugated
PDCD1
IgG1, kappa
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
5133
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