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CD279 (PD-1), clone: MIH4, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9969-82

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15218297

  • £95.23 / 100µg


EU Stock 1
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Description

Description

Description: The MIH4 monoclonal antibody reacts with the human PD-1 (programmed death-1), a 55kDa member of the immunoglobulin superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease. PD-1 is expressed predominantly on activated T and B lymphocytes. Two novel members of the B7 family have been identified as the PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. The MIH4 antibody recognizes a different epitope than antibody clones J105.Applications Reported: This MIH4 antibody has been reported for use in flow cytometric analysis, and immunohistology staining of frozen tissue sections.Applications Tested: This MIH4 antibody has been tested by flow cytometric analysis of PHA-stimulated peripheral blood mononuclear cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD279 (PD-1)
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q15116
PD1
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Frozen)
MIH4
Unconjugated
PDCD1
Purified
PDCD1
IgG1, kappa
100μg
Store at 2-8°C.
Primary
5133
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