CD279 (PD-1) Mouse anti-Human, Clone: MIH4, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9969-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15218297

Quantity Price
1 £ 91.11 / 100µg
EU Stock 2
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Description and Specification

Specification

Quantity 100μg
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate Unlabeled
Concentration 0.5mg/mL
Host Species Mouse
Monoclonal or Polyclonal Monoclonal
Species Reactivity Human
Regulatory Status RUO
Primary or Secondary Primary
Antigen CD279 (PD-1)
Isotype IgG1
Clone MIH4
Storage Requirements Store at 2-8°C.
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)

The MIH4 monoclonal antibody reacts with the human PD-1 (programmed death-1), a 55kDa member of the immunoglobulin superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease. PD-1 is expressed predominantly on activated T and B lymphocytes. Two novel members of the B7 family have been identified as the PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. The MIH4 antibody recognizes a different epitope than antibody clones J105.