CD279 (PD-1) Mouse anti-Human, Biotin, Clone: eBioJ105 (J105), eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 13-2799-80
Code : Z2
Additional Details : Weight : 0.25000kg
DescriptionThe J105 monoclonal antibody reacts with the human PD-1 (programmed death-1), a 55kDa member of the CD28 immunoglobulin superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease. PD-1 is expressed predominantly on activated T and B lymphocytes. Two novel members of the B7 family have been identified as the PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells.
Costaining experiments suggest that eBioJ105 recognizes a different epitope than MIH4 (cat. 11-9969).
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|Store at 2-8°C. Do not freeze.|