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CD278 (ICOS) Monoclonal Antibody (7E.17G9), PE-Cyanine7, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
£224.00
Specifications
Antigen | CD278 (ICOS) |
---|---|
Clone | 7E.17G9 |
Concentration | 0.2 mg/mL |
Applications | Flow Cytometry |
Classification | Monoclonal |
Description
Description: The 7E.17G9 monoclonal antibody reacts with mouse ICOS (Inducible COStimulatory molecule), a T cell specific molecule and a third member of the CD28/CTLA-4 family. A homodimer of 47-57 kDa, ICOS is expressed on activated T cells, has potent costimulatory activity for T cell activation and proliferation and is required for humoral immune response. ICOS binds to its ligand on activated APC including B cells called B7h/B7RP-1 and is thought to play a protective role in inflammatory autoimmune diseases. ICOS may be involved in the development of Th2 cells. Applications Reported: This 7E.17G9 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 7E.17G9 antibody has been tested by flow cytometric analysis of stimulated mouse splenocytes. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Light sensitivity: This tandem dye is sensitive photo-induced oxidation. Please protect this vial and stained samples from light. Fixation: Samples can be stored in IC Fixation Buffer (cat. 00-8222) (100 μL cell sample + 100 μL IC Fixation Buffer) or 1-step Fix/Lyse Solution (cat.
CD278 (ICOS) Monoclonal antibody specifically detects CD278 (ICOS) in Mouse samples. It is validated for Flow Cytometry.Specifications
CD278 (ICOS) | |
0.2 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
Q9WVS0 | |
IgG2b κ | |
Affinity chromatography | |
Antibody |
7E.17G9 | |
Flow Cytometry | |
PE-Cyanine7 | |
Rat | |
Mouse | |
54167 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! |
For Research Use Only.