CD278 (ICOS) Rat anti-Mouse, PE-Cy7, Clone: 7E.17G9, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-9942-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15528696

Quantity Price
1 £ 68.4 / 25µg
EU Stock 1
Add to basket


Description and Specification

Specification

Applications Flow Cytometry
Host Species Rat
Format Conjugated
Conjugate PE-Cy7
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen CD278 (ICOS)
Isotype IgG2b
Gene Alias Inducible T-cell co-stimulator
Regulatory Status RUO
Primary or Secondary Primary
Concentration 0.2mg/mL
Species Reactivity Mouse
Clone 7E.17G9
Quantity 25μg

The 7E.17G9 monoclonal antibody reacts with mouse ICOS (Inducible COStimulatory molecule), a T cell specific molecule and a third member of the CD28/CTLA-4 family. A homodimer of 47-57 kDa, ICOS is expressed on activated T cells, has potent costimulatory activity for T cell activation and proliferation and is required for humoral immune response. ICOS binds to its ligand on activated APC including B cells called B7h/B7RP-1 and is thought to play a protective role in inflammatory autoimmune diseases. ICOS may be involved in the development of Th2 cells.