CD278 (ICOS) Rat anti-Mouse, PE-Cy7, Clone: 7E.17G9, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-9942-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15538696

Quantity Price
1 £ 167.38 / 100µg
EU Stock 5
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Description and Specification

Specification

Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Species Reactivity Mouse
Antigen CD278 (ICOS)
Applications Flow Cytometry
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Regulatory Status RUO
Concentration 0.2mg/mL
Format Conjugated
Conjugate PE-Cy7
Quantity 100μg
Isotype IgG2b
Gene Alias Inducible T-cell co-stimulator
Host Species Rat
Clone 7E.17G9

The 7E.17G9 monoclonal antibody reacts with mouse ICOS (Inducible COStimulatory molecule), a T cell specific molecule and a third member of the CD28/CTLA-4 family. A homodimer of 47-57 kDa, ICOS is expressed on activated T cells, has potent costimulatory activity for T cell activation and proliferation and is required for humoral immune response. ICOS binds to its ligand on activated APC including B cells called B7h/B7RP-1 and is thought to play a protective role in inflammatory autoimmune diseases. ICOS may be involved in the development of Th2 cells.