CD278 (ICOS) Rat anti-Mouse, Clone: 7E.17G9, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-9942-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15218847

Quantity Price
1 £ 182.82 / 500µg
EU Stock 1
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Description and Specification

Specification

Formulation aqueous buffer, no sodium azide
Isotype IgG2b
Gene Alias Inducible T-cell co-stimulator
Storage Requirements Store at 2-8°C.
Applications Flow Cytometry
Applications Functional Assay
Format Purified
Regulatory Status RUO
Host Species Rat
Clone 7E.17G9
Concentration 1mg/mL
Quantity 500μg
Conjugate Unlabeled
Species Reactivity Mouse
Antigen CD278 (ICOS)
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The 7E.17G9 monoclonal antibody reacts with mouse ICOS (Inducible COStimulatory molecule), a T cell specific molecule and a third member of the CD28/CTLA-4 family. A homodimer of 47-57 kDa, ICOS is expressed on activated T cells, has potent costimulatory activity for T cell activation and proliferation and is required for humoral immune response. ICOS binds to its ligand on activated APC including B cells called B7h/B7RP-1 and is thought to play a protective role in inflammatory autoimmune diseases. ICOS may be involved in the development of Th2 cells.