CD278 (ICOS) Rat anti-Mouse, Clone: 7E.17G9, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-9942-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15208847

Quantity Price
1 £ 66.65 / 50µg
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Quantity 50μg
Host Species Rat
Isotype IgG2b
Format Purified
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Primary or Secondary Primary
Conjugate Unlabeled
Storage Requirements Store at 2-8°C.
Clone 7E.17G9
Concentration 1mg/mL
Species Reactivity Mouse
Gene Alias Inducible T-cell co-stimulator
Regulatory Status RUO
Applications Flow Cytometry
Applications Functional Assay
Antigen CD278 (ICOS)

The 7E.17G9 monoclonal antibody reacts with mouse ICOS (Inducible COStimulatory molecule), a T cell specific molecule and a third member of the CD28/CTLA-4 family. A homodimer of 47-57 kDa, ICOS is expressed on activated T cells, has potent costimulatory activity for T cell activation and proliferation and is required for humoral immune response. ICOS binds to its ligand on activated APC including B cells called B7h/B7RP-1 and is thought to play a protective role in inflammatory autoimmune diseases. ICOS may be involved in the development of Th2 cells.