CD278 (ICOS) Rat anti-Mouse, Clone: 7E.17G9, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9942-85

UNSPSC: 12352203

Code: Z2

Additional Details:
Additional Details: Weight: 0.50000kg



Disclaimers: For Research Use Only.

Product Code. 15154355

Quantity Price
1 £ 158.36 / 500µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Conjugate Unlabeled
Applications Flow Cytometry
Primary or Secondary Primary
Format Purified
Clone 7E.17G9
Gene Alias Inducible T-cell co-stimulator
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Species Reactivity Mouse
Isotype IgG2b
Regulatory Status RUO
Storage Requirements Store at 2-8°C.
Antigen CD278 (ICOS)
Host Species Rat
Quantity 500μg
Concentration 0.5mg/mL

The 7E.17G9 monoclonal antibody reacts with mouse ICOS (Inducible COStimulatory molecule), a T cell specific molecule and a third member of the CD28/CTLA-4 family. A homodimer of 47-57 kDa, ICOS is expressed on activated T cells, has potent costimulatory activity for T cell activation and proliferation and is required for humoral immune response. ICOS binds to its ligand on activated APC including B cells called B7h/B7RP-1 and is thought to play a protective role in inflammatory autoimmune diseases. ICOS may be involved in the development of Th2 cells.