CD278 (ICOS) Rat anti-Mouse, Biotin, Clone: 7E.17G9, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-9942-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15300130

Quantity Price
1 £ 176.7 / 500µg
EU Stock 2
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Description and Specification

Specification

Host Species Rat
Species Reactivity Mouse
Conjugate Biotin
Quantity 500μg
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone 7E.17G9
Isotype IgG2b
Regulatory Status RUO
Antigen CD278 (ICOS)
Concentration 0.5mg/mL
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Inducible T-cell co-stimulator
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze.
Format Conjugated

The 7E.17G9 monoclonal antibody reacts with mouse ICOS (Inducible COStimulatory molecule), a T cell specific molecule and a third member of the CD28/CTLA-4 family. A homodimer of 47-57 kDa, ICOS is expressed on activated T cells, has potent costimulatory activity for T cell activation and proliferation and is required for humoral immune response. ICOS binds to its ligand on activated APC including B cells called B7h/B7RP-1 and is thought to play a protective role in inflammatory autoimmune diseases. ICOS may be involved in the development of Th2 cells.