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CD278 (ICOS) Golden Syrian Hamster anti-Mouse, PerCP-eFluor 710, Clone: 15F9, eBioscience™

Golden Syrian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-9940-80

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15301410

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance


Description

Description

The 15F9 monoclonal antibody reacts with mouse ICOS (Inducible COStimulatory molecule), a T cell specific molecule and a third member of the CD28/CTLA-4 family. A homodimer of 47-57 kDa, ICOS is expressed on activated T cells, has potent costimulatory activity for T cell activation and proliferation and is required for humoral immune response. IOS binds to its ligand on activated APC including B cells called B7h/B7RP-1 and is thought to play a protective role in inflammatory autoimmune diseases. ICOS may be involved in the development of Th2 cells.

The 15F9 antibody is reported to have functional activity.
Specifications

Specifications

CD278 (ICOS)
15F9
PerCP-eFluor 710
Conjugated
IgG
RUO
Primary
Murine
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Golden Syrian Hamster
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
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For Research Use Only.