CD278 (ICOS) Golden Syrian Hamster anti-Mouse, PerCP-eFluor 710, Clone: 15F9, eBioscience™

Golden Syrian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-9940-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15301410

Quantity Price
1 £ 68.97 / 25µg
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Clone 15F9
Isotype IgG
Conjugate PerCP-eFluor 710
Host Species Golden Syrian Hamster
Antigen CD278 (ICOS)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Quantity 25μg
Species Reactivity Mouse
Concentration 0.2mg/mL
Format Conjugated

The 15F9 monoclonal antibody reacts with mouse ICOS (Inducible COStimulatory molecule), a T cell specific molecule and a third member of the CD28/CTLA-4 family. A homodimer of 47-57 kDa, ICOS is expressed on activated T cells, has potent costimulatory activity for T cell activation and proliferation and is required for humoral immune response. IOS binds to its ligand on activated APC including B cells called B7h/B7RP-1 and is thought to play a protective role in inflammatory autoimmune diseases. ICOS may be involved in the development of Th2 cells.

The 15F9 antibody is reported to have functional activity.