CD276 (B7-H3) Mouse anti-Human, PerCP-eFluor 710, Clone: 7-517, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-2769-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15579226

Quantity Price
1 £ 66.65 / 25 tests
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Isotype IgG1
Concentration 5μL (0.125μg)/test
Clone 7-517
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry
Regulatory Status RUO
Host Species Mouse
Conjugate PerCP-eFluor 710
Primary or Secondary Primary
Species Reactivity Human
Antigen CD276 (B7-H3)
Monoclonal or Polyclonal Monoclonal
Quantity 25 tests
Gene Alias B7 homolog 3
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Format Conjugated

This 7-517 monoclonal antibody reacts with human CD276, which is also known as B7-H3. This type I transmembrane protein is expressed on immature and mature dendritic cells but not monocytes, granulocytes, or resting lymphocytes. Moreover, CD276 is expressed on non-hematopoietic cells such as osteoblasts, fibroblasts, and epithelial cells. However, CD276 expression can be induced on dendritic cells, monocytes, T, B, and NK cells. This co-stimulatory molecule binds activated T cells, leading to cell proliferation and IFN-gamma production.