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CD274 (PD-L1, B7-H1) Mouse anti-Human, PerCP-eFluor™ 710, Clone: MIH1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-5983-41

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15569326

  • £89.50 / 25 tests

In stock, ready to ship: 1

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Description

Description

Our testing indicates that PerCP-eFluor® 710 conjugated antibodies are stable when stained samples are exposed to freshly prepared 2% formaldehyde overnight at 4°C, but please evaluate for alternative fixation protocols. Excitation: 488 nm; Emission: 710 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered. Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.
Specifications

Specifications

CD274 (PD-L1, B7-H1)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q9NZQ7
B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, B7 homolog 1, CD274 antigen, PDCD1 ligand 1, programmed cell death 1 ligand 1, programmed death ligand 1
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
MIH1
PerCP-eFluor™ 710
CD274
Liquid
CD274
IgG1, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
29126
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For Research Use Only.