missing translation for 'onlineSavingsMsg'
Learn More

CD273 (B7-DC) Rat anti-Mouse, Clone: TY25, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Brand:  Affymetrix eBioscience 16-5986-82

Code : Z2

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15248727

  • £133.91 / 100µg


EU Stock 3
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

The TY25 monoclonal antibody reacts with mouse B7-DC/PD-L2. B7-DC, a member of the B7 family, has a predicted molecular weight of ∽25kDa and belongs to the Ig superfamily. The mouse B7-DC has a short cytoplasmic tail (4aa). B7-DC is primarily expressed by sub-populations of dendritic cells, monocytes and macrophages. Although B7-DC has structural and sequence similarities to the B7 family, it does not bind CD28/CTLA-4, but binds PD-1. The interactions between PD-1 and B7-DC/PD-L2 have been reported to be involved in costimulation or suppression of T cell proliferation depending on state of cellular activation. TY25 is a useful tool to study the exact function of B7-DC/PD-L2 in APC/T cell interaction and to characterize the expression pattern of this molecule in mouse.
Specifications

Specifications

CD273 (B7-DC)
TY25
Unlabeled
Purified
Rat
100μg
Store at 2-8°C.
Monoclonal
Functional Assay
1mg/mL
aqueous buffer, no sodium azide
B7DC, PD-L2, PDL-2, PDL2
IgG2a
RUO
Primary
Murine