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CD273 (B7-DC) Rat anti-Mouse, Clone: TY25, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-5986-81

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15247667

  • £60.53 / 50µg


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For Research Use Only.


Specifications

Description

The TY25 monoclonal antibody reacts with mouse B7-DC/PD-L2. B7-DC, a member of the B7 family, has a predicted molecular weight of ∽25kDa and belongs to the Ig superfamily. The mouse B7-DC has a short cytoplasmic tail (4aa). B7-DC is primarily expressed by sub-populations of dendritic cells, monocytes and macrophages. Although B7-DC has structural and sequence similarities to the B7 family, it does not bind CD28/CTLA-4, but binds PD-1. The interactions between PD-1 and B7-DC/PD-L2 have been reported to be involved in costimulation or suppression of T cell proliferation depending on state of cellular activation. TY25 is a useful tool to study the exact function of B7-DC/PD-L2 in APC/T cell interaction and to characterize the expression pattern of this molecule in mouse.
Description & Specifications

Specifications

CD273 (B7-DC)
TY25
Unlabeled
Purified
Rat
50μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
B7DC, PD-L2, PDL-2, PDL2
IgG2a
RUO
Primary
Murine