missing translation for 'onlineSavingsMsg'
Learn More

CD273 (B7-DC), PE, clone: MIH18, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-5888-42

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15537046

  • £156.21 / 100 tests


EU Stock 8
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

Description: The MIH18 monoclonal antibody reacts with human B7-DC, also known as PD-L2. B7-DC, a recently identified member of the B7 family, has a predicted molecular weight of approximately 25kDa and belongs to the Ig superfamily. B7-DC is primarily expressed by subpopulations of dendritic cells and monocytes/macrophages. Although B7-DC has structural and sequence similarities to the B7 family, it does not bind CD28/CTLA-4, rather it is a ligand for PD-1. The interactions between PD-1 and B7-DC/PD-L2 have been reported to be involved in costimulation or suppression of T cell proliferation depending on state of cellular activation. MIH18 is a useful tool for studies to elucidate the exact function of B7-DC/PD-L2 in APC/T cell interaction and to characterize the expression pattern of this molecule in humans. MIH18 is a blocking antibody.Applications Reported: The MIH18 antibody has been reported for use in flow cytometric analysis.Applications Tested: This MIH18 antibody has been pre-titrated and tested by flow cytometric analysis of mature dendritic cells and normal human peripheral blood cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD273 (B7-DC)
MIH18
PE
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.125μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
PD-L2
IgG1
RUO
Primary
Human
Videos