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CD27 Armenian Hamster anti-Human, Mouse, Clone: LG.3A10, Functional Grade, eBioscience™

Armenian Hamster Monoclonal Antibody, Functional Grade

Brand:  Affymetrix eBioscience 16-0272-85

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15288407

  • £201.16 / 500µg


Estimated Shipment
07-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The LG.3A10 monoclonal antibody reacts with mouse CD27, a lymphocyte-specific member of the TNFR superfamily. CD27 is expressed by virtually all mature T cells and by a subpopulation of B cells, mainly memory B cells. In mouse, CD27 has been found on nearly all thymocytes excluding a population of CD46-CD8- precursors. CD27 binds to CD70 and, through this interaction, plays an important role in T cell-B cell interaction. It has been reported that triggering CD27 plays an important role in the maturation of CD4+ and CD8+ effector cells. LG.8F10 cross-reacts with human and rat CD27.
When the monoclonal antibody LG.3A10 is crosslinked on purified T cells, proliferation is increased. In the absence of crosslinking, the antibody inhibits CD27-CD70 interaction.
Description & Specifications

Specifications

CD27
LG.3A10
Unlabeled
aqueous buffer, no sodium azide
Armenian Hamster
500μg
Store at 2-8°C.
Monoclonal
Immunohistochemistry (Frozen)
1mg/mL
Purified
TNFRSF7
IgG
RUO
Primary
Murine