CD27 Armenian Hamster anti-Human, Mouse, Clone: LG.3A10, Functional Grade, eBioscience™

Armenian Hamster Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0272-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15288407

Quantity Price
1 £ 201.16 / 500µg
Estimated Shipment date
from Supplier 04-05-2017
Add to basket


Description and Specification

Specification

Clone LG.3A10
Species Reactivity Human, Mouse
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry (Frozen)
Gene Alias TNFRSF7
Formulation aqueous buffer, no sodium azide
Regulatory Status RUO
Quantity 500μg
Concentration 1mg/mL
Monoclonal or Polyclonal Monoclonal
Host Species Armenian Hamster
Conjugate Unlabeled
Primary or Secondary Primary
Isotype IgG
Antigen CD27
Storage Requirements Store at 2-8°C.
Format Purified

The LG.3A10 monoclonal antibody reacts with mouse CD27, a lymphocyte-specific member of the TNFR superfamily. CD27 is expressed by virtually all mature T cells and by a subpopulation of B cells, mainly memory B cells. In mouse, CD27 has been found on nearly all thymocytes excluding a population of CD46-CD8- precursors. CD27 binds to CD70 and, through this interaction, plays an important role in T cell-B cell interaction. It has been reported that triggering CD27 plays an important role in the maturation of CD4+ and CD8+ effector cells. LG.8F10 cross-reacts with human and rat CD27.
When the monoclonal antibody LG.3A10 is crosslinked on purified T cells, proliferation is increased. In the absence of crosslinking, the antibody inhibits CD27-CD70 interaction.