CD268 (BAFF Receptor) Rat anti-Mouse, APC, Clone: eBio7H22-E16, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-5943-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15300800

Quantity Price
1 £ 78.88 / 25µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Clone eBio7H22-E16
Quantity 25μg
Isotype IgG1
Species Reactivity Mouse
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Gene Alias BAFFR, BAFF-R, TNFRSF13C, BCMD, BR3, BlySR3
Conjugate APC
Host Species Rat
Concentration 0.2mg/mL
Format Conjugated
Applications Flow Cytometry
Antigen CD268 (BAFF Receptor)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The monoclonal antibody eBio7H22.E16 reacts with mouse BAFF-Receptor, a type III transmembrane TNF receptor family member. BAFF-R was found to be the predominant BAFF receptor expressed on peripheral B cells, in both humans and mice. The receptor is found on the surface of all B220+ B cells found in spleen. BAFF-R is expressed on activated/memory subsets of T-cells and is important for splenic B cell maturation and survival and is a major mediator of BAFF- dependent costimulatory responses in peripheral B and T cells. BAFF-R can cause a high level of autoimmune disease and a defect in BAFF-R will cause a decrease in generating mature B-Cells The ligand for the BAFF-R is BAFF also known as BLyS.