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CD268 (BAFF Receptor) Monoclonal Antibody (8A7), eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

£79.50 - £205.00

Specifications

Antigen CD268 (BAFF Receptor)
Clone 8A7
Concentration 0.5 mg/mL
Applications Flow Cytometry, Immunohistochemistry, Western Blot
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15208157
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Affymetrix eBioscience
14-9117-82
100 μg
£205.00
100µg
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15298147
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Affymetrix eBioscience
14-9117-80
25 μg This item is currently unavailable or has been discontinued.
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Description

Description

Description: The 8A7 monoclonal antibody reacts with the human BAFF receptor, also known as B lymphocyte stimulator (BLyS protein) receptor, which is expressed on B cells. The ligand for this receptor, BAFF (B cell-activating factor of the TNF family) is a B cell survival factor and regulates CD21/35 and CD23 expression. Interaction of this ligand with its receptor causes elevated CD21/35 and CD23 expression, whereas receptor blockade has been shown to down-modulate expression. Applications Reported: The 8A7 antibody has been reported for use in flow cytometric analysis, immunoblotting (WB), and immunohistochemical staining. It has also been reported for use in functional assays. (Please use Functional Grade purified 8A7, cat. 16-9117, in functional assays.). Applications Tested: The 8A7 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.

Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), also known as BAFFR, is a protein in humans is encoded by the TNFRSF13C gene. The BAFFR gene is mapped to chromosome 22q13. 1-q13. 31. It has got 184 amino acid transmembrane protein which is 56% identical to the mouse protein. B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF plays a crucial role in B cell development and can function through receptors other than BCMA.
Specifications

Specifications

CD268 (BAFF Receptor)
0.5 mg/mL
Monoclonal
Liquid
RUO
Q96RJ3
TNFRSF13C
Primary
4° C
TNFRSF13C
8A7
Flow Cytometry, Immunohistochemistry, Western Blot
Unconjugated
Mouse
Human
115650
IgG2a κ
Affinity chromatography
Antibody
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