CD267 (TACI) Rat anti-Mouse, APC, Clone: ebio8F10-3, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-5942-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15390790

Quantity Price
1 £ 109.45 / 100µg
EU Stock 4
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Description and Specification

Specification

Format Conjugated
Primary or Secondary Primary
Conjugate APC
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Antigen CD267 (TACI)
Isotype IgG2a
Gene Alias TNFRSF13B
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Applications Flow Cytometry
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL
Clone ebio8F10-3
Host Species Rat
Species Reactivity Mouse
Quantity 100μg

The monoclonal antibody eBio8F10.3 recognizes TACI (Transmembrane Activator and Calcium-modulator and CAML Interactor) also known as CD267. TACI is a type III membrane protein belonging to the TNF receptor superfamily. The ligand for TACI has been shown to be BAFF (BLyS) and APRIL. TACI is expressed on the surface of a subset of maturing splenic B cells of the transitional type termed T2. Genetic studies have shown a role for TACI in both stimulation and inhibition of B cell proliferation. This actual role for TACI in the mouse has still not been determined. Recently human TACI has been shown to have repressive activities which inhibit BAFF-R function.