CD267 (TACI) Rat anti-Mouse, APC, Clone: ebio8F10-3, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-5942-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15380790

Quantity Price
1 £ 60.53 / 50µg
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Isotype IgG2a
Format Conjugated
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Conjugate APC
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Mouse
Applications Flow Cytometry
Concentration 0.2mg/mL
Clone ebio8F10-3
Antigen CD267 (TACI)
Quantity 50μg
Regulatory Status RUO
Gene Alias TNFRSF13B
Host Species Rat
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.

The monoclonal antibody eBio8F10.3 recognizes TACI (Transmembrane Activator and Calcium-modulator and CAML Interactor) also known as CD267. TACI is a type III membrane protein belonging to the TNF receptor superfamily. The ligand for TACI has been shown to be BAFF (BLyS) and APRIL. TACI is expressed on the surface of a subset of maturing splenic B cells of the transitional type termed T2. Genetic studies have shown a role for TACI in both stimulation and inhibition of B cell proliferation. This actual role for TACI in the mouse has still not been determined. Recently human TACI has been shown to have repressive activities which inhibit BAFF-R function.