CD267 (TACI) Mouse anti-Human, PE, Clone: 11H3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-9217-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15527196

Quantity Price
1 £ 170.59 / 100 tests
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Host Species Murine
Quantity 100 Tests
Applications Flow Cytometry
Conjugate PE
Clone 11H3
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Gene Alias TNFRSF13B
Regulatory Status RUO
Species Reactivity Human
Antigen CD267 (TACI)
Isotype IgG2a
Format Conjugated
Concentration 5μL (0.25μg)/test
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The 11H3 antibody reacts with human TACI, also known as tumor necrosis factor receptor 13B. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases. TACI mRNA and protein are found predominantly in B-cells and correlate with BLyS binding in a panel of B-cell lines. TACI interacts with nanomolar affinity with the BLyS-related tumor necrosis factor homologue APRIL for which no clear in vivo role has been described. 11H3 does not block binding of BAFF/BLyS to TACI.