missing translation for 'onlineSavingsMsg'
Learn More

CD267 (TACI) Mouse anti-Human, Clone: 11H3, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9217-82

Code : Z2

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15288157

  • £121.67 / 100µg


Call for latest availability
+44 (0)1509 555 500
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

The 11H3 antibody reacts with human TACI, also known as tumor necrosis factor receptor 13B. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases. TACI mRNA and protein are found predominantly in B-cells and correlate with BLyS binding in a panel of B-cell lines. TACI interacts with nanomolar affinity with the BLyS-related tumor necrosis factor homologue APRIL for which no clear in vivo role has been described. 11H3 does not block binding of BAFF/BLyS to TACI.
Specifications

Specifications

CD267 (TACI)
11H3
Unconjugated
Purified
Murine
100μg
Store at 2-8°C.
Monoclonal
Functional Assay
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
TNFRSF13B
IgG2a
RUO
Primary
Human
Videos