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CD267 (TACI), clone: 11H3, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9217-82

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15288157

  • £125.88 / 100µg


Estimated Shipment
01-03-2018
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Disclaimers:

For Research Use Only.


Description

Description

Description: The 11H3 antibody reacts with human TACI, also known as tumor necrosis factor receptor 13B. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases. TACI mRNA and protein are found predominantly in B-cells and correlate with BLyS binding in a panel of B-cell lines. TACI interacts with nanomolar affinity with the BLyS-related tumor necrosis factor homologue APRIL for which no clear in vivo role has been described. 11H3 does not block binding of BAFF/BLyS to TACI.Applications Reported: This 11H3 antibody has been reported for use in flow cytometric analysis. (Please use Functional Grade purified 11H3, cat. 16-9217, in functional assays.).Applications Tested: This 11H3 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD267 (TACI)
11H3
Unconjugated
Purified
Murine
100μg
Store at 2-8°C.
Monoclonal
Functional Assay
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
TNFRSF13B
IgG2a
RUO
Primary
Human
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