CD267 (TACI) Mouse anti-Human, Clone: 11H3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9217-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15288157

Quantity Price
1 £ 121.67 / 100µg
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Host Species Murine
Isotype IgG2a
Applications Flow Cytometry
Applications Functional Assay
Clone 11H3
Conjugate Unlabeled
Storage Requirements Store at 2-8°C.
Concentration 0.5mg/mL
Format Purified
Species Reactivity Human
Quantity 100μg
Primary or Secondary Primary
Antigen CD267 (TACI)
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias TNFRSF13B

The 11H3 antibody reacts with human TACI, also known as tumor necrosis factor receptor 13B. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases. TACI mRNA and protein are found predominantly in B-cells and correlate with BLyS binding in a panel of B-cell lines. TACI interacts with nanomolar affinity with the BLyS-related tumor necrosis factor homologue APRIL for which no clear in vivo role has been described. 11H3 does not block binding of BAFF/BLyS to TACI.