missing translation for 'onlineSavingsMsg'
Learn More

CD26 Rat anti-Mouse, PerCP-Cy5.5, Clone: H194-112 (H194-112.12.4.4.5), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 45-0261-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

 View more versions of this product

Product Code. 15381150

  • £182.82 / 100ยตg


Call for latest availability
+44 (0)1509 555 500
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

The monoclonal antibody H194-112 recognizes mouse CD26, a thymocyte-activating molecule (THAM). CD26 is a surface expressed and soluble ectoenzyme (dipeptidyl peptidase IV) that cleaves dipeptides from the amino terminus of proteins. In particular CD26 has been shown to cleave CXCL12, CCL22, neuropeptide Y and glucagon. CD26 is involved in adhesion, apoptosis, disease regulation, and engraftment. Expression is regulated during thymic development at the messenger RNA level. Additionally, CD26 protein is found on thymocytes, a percentage of resting B cells, stimulated B cells, NK cells and a percentage of resting and activated T cells and other epithelial cell types. On human cells more CD26 protein is found on Th2 cells. Functional CD26 is expressed on Sca-1+c-Kit+lin- cells. This expression has been shown to correlate with mobilization of progenitor cells. Inhibition of CD26 activity through a variety of compounds enhances allogenic stem cell homing and engraftment.

This antibody is reported to have activating function.
Specifications

Specifications

CD26
H194-112 (H194-112.12.4.4.5)
PerCP-Cy5.5
Conjugated
Rat
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Dipeptidyl Peptidase IV, DPPIV, DPP4,
IgG2a
RUO
Primary
Murine