CD26, PerCP-Cyanine5.5, clone: H194-112 (H194-126.96.36.199.5), eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 45-0261-80
Code : Z2
Additional Details : Weight : 0.25000kg
DescriptionDescription: The monoclonal antibody H194-112 recognizes mouse CD26, a thymocyte-activating molecule (THAM). CD26 is a surface expressed and soluble ectoenzyme (dipeptidyl peptidase IV) that cleaves dipeptides from the amino terminus of proteins. In particular CD26 has been shown to cleave CXCL12, CCL22, neuropeptide Y and glucagon. CD26 is involved in adhesion, apoptosis, disease regulation, and engraftment. Expression is regulated during thymic development at the messenger RNA level. Additionally, CD26 protein is found on thymocytes, a percentage of resting B cells, stimulated B cells, NK cells and a percentage of resting and activated T cells and other epithelial cell types. On human cells more CD26 protein is found on Th2 cells. Functional CD26 is expressed on Sca-1+c-Kit+lin- cells. This expression has been shown to correlate with mobilization of progenitor cells. Inhibition of CD26 activity through a variety of compounds enhances allogenic stem cell homing and engraftment. This antibody is reported to have activating function.Applications Reported: This H194-112 (H194-188.8.131.52.5) antibody has been reported for use in flow cytometric analysis.Applications Tested: This H194-112 (H194-184.108.40.206.5) antibody has been tested by flow cytometric analysis of mouse splenocytes or thymocytes. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488 nm; Emission: 695 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|Dipeptidyl Peptidase IV, DPPIV, DPP4,|
For Research Use Only.