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CD258 (LIGHT) Mouse anti-Human, PE, Clone: 7-3 (7), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-2589-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15506956

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Disclaimers:

For Research Use Only.


Description

Description

This 7-3 (7) monoclonal antibody reacts with human CD258 (also known as LIGHT), a 29kDa type II transmembrane protein that is a member of the TNF ligand superfamily related to lymphotoxin-ß (LT-ß). Expressed on activated T cells, particularly CD8+ T cells, LIGHT plays a role in cell survival, inflammation, and tumor eradication. Furthermore, upon binding its ligand, herpesvirus entry mediator (HVEM), LIGHT induces a costimulatory effect on T cells, enhancing T cell proliferation and cytokine production. LIGHT has also been shown to indirectly interact with the LT-ß receptor.
Specifications

Specifications

CD258 (LIGHT)
7-3 (7)
PE
Conjugated
IgG1
RUO
Primary
Human
Flow Cytometry
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal