CD258 (LIGHT) Mouse anti-Human, PE, Clone: 7-3 (7), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-2589-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15506956

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Description and Specification

Specification

Quantity 25 tests
Concentration 5μL (0.25μg)/test
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Primary or Secondary Primary
Isotype IgG1
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Applications Flow Cytometry
Conjugate PE
Monoclonal or Polyclonal Monoclonal
Clone 7-3 (7)
Species Reactivity Human
Host Species Mouse
Antigen CD258 (LIGHT)
Format Conjugated

This 7-3 (7) monoclonal antibody reacts with human CD258 (also known as LIGHT), a 29kDa type II transmembrane protein that is a member of the TNF ligand superfamily related to lymphotoxin-ß (LT-ß). Expressed on activated T cells, particularly CD8+ T cells, LIGHT plays a role in cell survival, inflammation, and tumor eradication. Furthermore, upon binding its ligand, herpesvirus entry mediator (HVEM), LIGHT induces a costimulatory effect on T cells, enhancing T cell proliferation and cytokine production. LIGHT has also been shown to indirectly interact with the LT-ß receptor.