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CD258 (LIGHT), PE, clone: 7-3 (7), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-2589-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15516956

  • £186.79 / 100 tests


Estimated Shipment date
from Supplier 30-07-2018
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Description

Description

Description: This 7-3 (7) monoclonal antibody reacts with human CD258 (also known as LIGHT), a 29-kDa type II transmembrane protein that is a member of the TNF ligand superfamily related to lymphotoxin-β (LT-β). Expressed on activated T cells, particularly CD8+ T cells, LIGHT plays a role in cell survival, inflammation, and tumor eradication. Furthermore, upon binding its ligand, herpesvirus entry mediator (HVEM), LIGHT induces a costimulatory effect on T cells, enhancing T cell proliferation and cytokine production. LIGHT has also been shown to indirectly interact with the LT-β receptor.Applications Reported: This 7-3 (7) antibody has been reported for use in flow cytometric analysis.Applications Tested: This 7-3 (7) antibody has been pre-titrated and tested by flow cytometric analysis on PMA- and ionomycin-stimulated normal human peripheral blood cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD258 (LIGHT)
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
O43557
TNFSF14, tumor necrosis factor (ligand) superfamily, member 14, CD258, HVEML, LIGHT, LTg, TR2, delta transmembrane LIGHT, herpesvirus entry mediator A, ligand for herpesvirus entry mediator, tumor necrosis factor ligand superfamily, member 14, tumor necrosis factor receptor-like 2, tumor necrosis factor superfamily member LIGHT
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
7-3 (7)
PE
TNFSF14
Conjugated
TNFSF14
IgG1, kappa
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
8740
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