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CD258 (LIGHT) Mouse anti-Human, APC, Clone: 7-3 (7), eBioscience™

Mouse Monoclonal Antibody

£91.50 - £210.00

Specifications

Antigen CD258 (LIGHT)
Clone 7-3 (7)
Target Species Human
Conjugate APC
Isotype IgG1, kappa
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15558066
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Affymetrix eBioscience
17-2589-41
25 Tests £91.50
25 tests View alternative products
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Estimated Shipment
30-11-2020
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15568066
View Documents
Affymetrix eBioscience
17-2589-42
100 Tests £210.00
100 tests View alternative products
Save Up to 
»
Estimated Shipment
03-11-2020
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Description

Description

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF (tumor necrosis factor) and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 (tumor necrosis factor receptor 1) and Fas. Cell death signals are transduced by death domain (DD)-containing adapter molecules and members of the ICE (interleukin-1-beta converting enzyme)/CED-3 (C. elegans death receptor-3) protease family. A novel DD-containing molecule was recently cloned from mouse, human and monkey and designated Daxx (death associated protein 6). Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway. Daxx is widely expressed in fetal and adult human and mouse tissues indicating its important function in Fas signaling pathways.
Specifications

Specifications

CD258 (LIGHT)
Human
IgG1, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
7-3 (7)
APC
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.