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CD258 (LIGHT) Mouse anti-Human, APC, Clone: 7-3 (7), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-2589-41

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15558066

  • £91.50 / 25 tests

Estimated Shipment
05-01-2021

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Description

Description

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF (tumor necrosis factor) and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 (tumor necrosis factor receptor 1) and Fas. Cell death signals are transduced by death domain (DD)-containing adapter molecules and members of the ICE (interleukin-1-beta converting enzyme)/CED-3 (C. elegans death receptor-3) protease family. A novel DD-containing molecule was recently cloned from mouse, human and monkey and designated Daxx (death associated protein 6). Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway. Daxx is widely expressed in fetal and adult human and mouse tissues indicating its important function in Fas signaling pathways.
Specifications

Specifications

CD258 (LIGHT)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
O43557
TNFSF14; tumor necrosis factor (ligand) superfamily, member 14; CD258; HVEML; LIGHT; LTg; TR2; delta transmembrane LIGHT; herpesvirus entry mediator A; ligand for herpesvirus entry mediator; tumor necrosis factor ligand superfamily, member 14; tumor necrosis factor receptor-like 2; tumor necrosis factor superfamily member LIGHT
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
7-3 (7)
APC
TNFSF14
Liquid
TNFSF14
IgG1, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
8740
Videos
SDS
Documents

For Research Use Only.