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CD258 (LIGHT), APC, clone: 7-3 (7), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-2589-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15558066

  • £87.01 / 25 tests


Estimated Shipment date
from Supplier 22-02-2018
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Disclaimers:

For Research Use Only.


Description

Description

Description: This 7-3 (7) monoclonal antibody reacts with human CD258 (also known as LIGHT), a 29-kDa type II transmembrane protein that is a member of the TNF ligand superfamily related to lymphotoxin-β (LT-β). Expressed on activated T cells, particularly CD8+ T cells, LIGHT plays a role in cell survival, inflammation, and tumor eradication. Furthermore, upon binding its ligand, herpesvirus entry mediator (HVEM), LIGHT induces a costimulatory effect on T cells, enhancing T cell proliferation and cytokine production. LIGHT has also been shown to indirectly interact with the LT-β receptor.Applications Reported: This 7-3 (7) antibody has been reported for use in flow cytometric analysis.Applications Tested: This 7-3 (7) antibody has been tested by flow cytometric analysis on PMA- and ionomycin-stimulated normal human peripheral blood cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD258 (LIGHT)
7-3 (7)
APC
Conjugated
IgG1
RUO
Primary
Human
Flow Cytometry
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
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