CD25 Rat anti-Mouse, eFluor 450, Clone: PC61.5, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-0251-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15381700

Quantity Price
1 £ 121.67 / 100µg
EU Stock 3
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Description and Specification

Specification

Host Species Rat
Gene Alias Interleukin-2 Receptor alpha
Monoclonal or Polyclonal Monoclonal
Antigen CD25
Conjugate eFluor 450
Clone PC61.5
Quantity 100μg
Species Reactivity Mouse
Applications Flow Cytometry
Primary or Secondary Primary
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Concentration 0.2mg/mL
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Isotype IgG1
Regulatory Status RUO

The PC61.5 antibody reacts with mouse CD25, the 55kDa interleukin-2 receptor alpha chain (IL-2R alpha). CD25 is expressed by early progenitors of the T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor. Binding of IL-2 to both the high and low affinity classes of IL-2 receptor is inhibited by the PC61.5 antibody. CD25 plays a role in lymphocyte differentiation and activation/proliferation.