CD25 Rat anti-Mouse, Clone: PC61.5, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0251-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15256867

Quantity Price
1 £ 29.97 / 50µg
Estimated Shipment date
from Supplier 08-05-2017
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Description and Specification

Specification

Applications Flow Cytometry
Storage Requirements Store at 2-8°C.
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Species Reactivity Mouse
Gene Alias Interleukin-2 Receptor alpha
Concentration 0.5mg/mL
Clone PC61.5
Antigen CD25
Isotype IgG1
Regulatory Status RUO
Primary or Secondary Primary
Conjugate Unlabeled
Quantity 50μg
Host Species Rat
Format Purified

The PC61.5 antibody reacts with mouse CD25, the 55kDa interleukin-2 receptor alpha chain (IL-2R alpha). CD25 is expressed by early progenitors of the T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor. Binding of IL-2 to both the high and low affinity classes of IL-2 receptor is inhibited by the PC61.5 antibody. CD25 plays a role in lymphocyte differentiation and activation/proliferation.