CD25 Rat anti-Mouse, Biotin, Clone: PC61.5, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-0251-86

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15289499

Quantity Price
1 £ 243.96 / 1mg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Concentration 0.5mg/mL
Monoclonal or Polyclonal Monoclonal
Gene Alias Interleukin-2 Receptor alpha
Storage Requirements Store at 2-8°C. Do not freeze.
Format Conjugated
Isotype IgG1
Species Reactivity Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 1mg
Regulatory Status RUO
Primary or Secondary Primary
Antigen CD25
Conjugate Biotin
Host Species Rat
Clone PC61.5
Applications Flow Cytometry

The PC61.5 antibody reacts with mouse CD25, the 55kDa interleukin-2 receptor alpha chain (IL-2R alpha). CD25 is expressed by early progenitors of the T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor. Binding of IL-2 to both the high and low affinity classes of IL-2 receptor is inhibited by the PC61.5 antibody. CD25 plays a role in lymphocyte differentiation and activation/proliferation.