CD25 Rat anti-Mouse, Alexa Fluor 700, Clone: PC61.5, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 56-0251-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15322120

Quantity Price
1 £ 55.0 / 25µg
EU Stock 1
Add to basket


Description and Specification

Specification

Isotype IgG1
Clone PC61.5
Species Reactivity Mouse
Conjugate Alexa Fluor 700
Regulatory Status RUO
Antigen CD25
Primary or Secondary Primary
Host Species Rat
Monoclonal or Polyclonal Monoclonal
Quantity 25μg
Concentration 0.2mg/mL
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Gene Alias Interleukin-2 Receptor alpha
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Format Conjugated

The PC61.5 antibody reacts with mouse CD25, the 55kDa interleukin-2 receptor alpha chain (IL-2R alpha). CD25 is expressed by early progenitors of the T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor. Binding of IL-2 to both the high and low affinity classes of IL-2 receptor is inhibited by the PC61.5 antibody. CD25 plays a role in lymphocyte differentiation and activation/proliferation.