CD25 Rat anti-Mouse, Alexa Fluor 700, Clone: PC61.5, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 56-0251-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15332120

Quantity Price
1 £ 123.42 / 100µg
EU Stock 3
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Description and Specification

Specification

Concentration 0.2mg/mL
Isotype IgG1
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen CD25
Applications Flow Cytometry
Gene Alias Interleukin-2 Receptor alpha
Clone PC61.5
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Conjugate Alexa Fluor 700
Host Species Rat
Species Reactivity Mouse
Quantity 100μg
Regulatory Status RUO
Format Conjugated

The PC61.5 antibody reacts with mouse CD25, the 55kDa interleukin-2 receptor alpha chain (IL-2R alpha). CD25 is expressed by early progenitors of the T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor. Binding of IL-2 to both the high and low affinity classes of IL-2 receptor is inhibited by the PC61.5 antibody. CD25 plays a role in lymphocyte differentiation and activation/proliferation.