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CD25 Rat anti-Mouse, Alexa Fluor 488, Clone: 3C7, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-0253-80

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15351990

  • £54.42 / 25µg


EU Stock 4
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Disclaimers:

For Research Use Only.


Specifications

Description

The eBio3C7 antibody reacts with mouse CD25, the 55kDa interleukin-2 receptor a chain (IL-2Ra). CD25 is expressed by early progenitors of the T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common γ chain) to form the high affinity IL-2 receptor. Binding of IL-2 to both the high and low affinity classes of the IL-2 receptor is inhibited by the 3C7 antibody. CD25 plays a role in lymphocyte differentiation and activation/proliferation. The epitopes recognized by eBio3C7, PC61.5 and eBio7D4 are all different allowing for depletion with one antibody (typically PC61.5) and subsequent detection with another CD25 antibody.
Description & Specifications

Specifications

CD25
eBio3C7 (3C7)
Alexa Fluor 488
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Rat
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.5mg/mL
Conjugated
Interleukin-2 Receptor alpha, IL-2Ra, IL2Ra
IgG2b
RUO
Primary
Murine