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CD25 Rat anti-Mouse, Alexa Fluor 488, Clone: 3C7, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-0253-82

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15361990

  • £121.67 / 100µg


EU Stock 4
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Disclaimers:

For Research Use Only.


Description

Description

The eBio3C7 antibody reacts with mouse CD25, the 55kDa interleukin-2 receptor a chain (IL-2Ra). CD25 is expressed by early progenitors of the T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common γ chain) to form the high affinity IL-2 receptor. Binding of IL-2 to both the high and low affinity classes of the IL-2 receptor is inhibited by the 3C7 antibody. CD25 plays a role in lymphocyte differentiation and activation/proliferation. The epitopes recognized by eBio3C7, PC61.5 and eBio7D4 are all different allowing for depletion with one antibody (typically PC61.5) and subsequent detection with another CD25 antibody.
Specifications

Specifications

CD25
eBio3C7 (3C7)
Alexa Fluor™ 488
Conjugated
Rat
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Interleukin-2 Receptor alpha, IL-2Ra, IL2Ra
IgG2b
RUO
Primary
Murine
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