CD25 Mouse anti-Rat, PE, Clone: OX39, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-0390-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15258519

Quantity Price
1 £ 61.11 / 100µg
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Host Species Mouse
Species Reactivity Rat
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone OX39
Gene Alias Interleukin-2 Receptor alpha, IL-2Ra
Primary or Secondary Primary
Applications Flow Cytometry
Monoclonal or Polyclonal Monoclonal
Format Conjugated
Quantity 100μg
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen CD25
Regulatory Status RUO
Conjugate PE
Concentration 0.2mg/mL
Isotype IgG1

The OX39 monoclonal antibody reacts with mouse CD25, the 55kDa interleukin-2 receptor alpha (IL-2R alpha). CD25 is expressed by early progenitors of the T and B lineages as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor. CD25 plays a role in lymphocyte differentiation and activation/proliferation.

The OX39 clone has been shown to deplete CD25 cells in vivo.