CD25 Mouse anti-Rat, Biotin, Clone: OX39, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-0390-85

500UG ANTI-RAT CD25 BIOTIN

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15269539

Quantity Price
1 £ 176.0 / 500µg
Estimated Shipment date
from Supplier 08-12-2016
Add to basket


Description and Specification

Specification

Antigen CD25
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Clone OX39
Concentration 0.5mg/mL
Conjugate Biotin
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Interleukin-2 Receptor alpha, IL-2Ra
Host Species Mouse
Isotype IgG1
Quantity 500μg
Regulatory Status RUO
Species Reactivity Rat
Storage Requirements Store at 2-8°C. Do not freeze.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The OX39 monoclonal antibody reacts with mouse CD25, the 55kDa interleukin-2 receptor alpha (IL-2R alpha). CD25 is expressed by early progenitors of the T and B lineages as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor. CD25 plays a role in lymphocyte differentiation and activation/proliferation.

The OX39 clone has been shown to deplete CD25 cells in vivo.