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CD25 Mouse anti-Canine, PE, Clone: P4A10, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-0250-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15566736

  • £66.36 / 25 tests


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For Research Use Only.


Description

Description

This P4A10 monoclonal antibody reacts with canine CD25, the 55kDa interleukin-2 receptor alpha (IL-2Rα) chain. As in humans and mice, CD25 in dogs is expressed by early T and B lineage progenitors as well as by activated mature T and B lymphocytes. CD25 associates with the IL-2R beta (CD122) and gamma (CD132) chains to form the high-affinity IL-2 receptor. On its own, CD25 binds IL-2 with low affinity. Along with CD4 and Foxp3, CD25 is a major marker used to define regulatory T cells.

The P4A10 antibody has been reported to recognize the same epitope as the anti-human CD25 monoclonal antibody ACT-1, but with greater affinity.
Specifications

Specifications

CD25
P4A10
PE
Conjugated
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Interleukin-2 Receptor alpha
IgG1
RUO
Primary
Canine
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