CD25 Mouse anti-Canine, eFluor 660, Clone: P4A10, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-0250-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15519876

Quantity Price
1 £ 152.25 / 100 tests
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Conjugate eFluor 660
Quantity 100 tests
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Isotype IgG1
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Clone P4A10
Concentration 5μL (0.125μg)/test
Antigen CD25
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Applications Flow Cytometry
Primary or Secondary Primary
Format Conjugated
Gene Alias Interleukin-2 Receptor alpha, IL-2Ra, IL2Ra
Species Reactivity Canine

This P4A10 monoclonal antibody reacts with canine CD25, the 55kDa interleukin-2 receptor alpha (IL-2Rα) chain. As in humans and mice, CD25 in dogs is expressed by early T and B lineage progenitors as well as by activated mature T and B lymphocytes. CD25 associates with the IL-2R beta (CD122) and gamma (CD132) chains to form the high-affinity IL-2 receptor. On its own, CD25 binds IL-2 with low affinity. Along with CD4 and Foxp3, CD25 is a major marker used to define regulatory T cells.

The P4A10 antibody has been reported to recognize the same epitope as the anti-human CD25 monoclonal antibody ACT-1, but with greater affinity.