CD247 (CD3 zeta) Mouse anti-Human, PerCP-eFluor 710, Clone: 6B10.2, eBioscience™

Mouse Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-2479-42

100TEST Anti-Human CD247 (CD3 zeta) PerCP-eFluor710

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg

Disclaimers: For Research Use Only.

Product Code. 15559226

Quantity Price
1 £326.90 / 100 tests
Estimated Shipment date
from Supplier 28-10-2016
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Description and Specification


Antigen CD247 (CD3 zeta)
Applications Flow Cytometry (Intracellular Staining)
Clone 6B10.2
Concentration 5μL (0.03μg)/test
Conjugate PerCP-eFluor 710
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Isotype IgG1
Quantity 100 tests
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

This 6B10.2 monoclonal antibody reacts with human CD247, which is also known as the invariant zeta chain. The CD3 complex is composed of three monomeric chains (γ, δ, and ε) and the invariant zeta chain, which exists as a homodimer or as a heterodimer with the η subunit. Together with the T cell antigen receptor (TCR), the CD3 γ, δ, ε, and zeta chains comprise the TCR/CD3 complex. CD3 zeta is expressed on immature and mature thymocytes, as well as T lymphocytes and NK cells. Signal transduction during T cell activation is mediated by tyrosine phosphorylation of cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs) present on the zeta chain.

The 6B10.2 monoclonal antibody recognizes a transmembrane epitope of the CD3 zeta chain. Therefore, flow cytometric analysis with this antibody requires intracellular staining. In addition, this antibody has been reported to recognize the zeta chain as a homodimer but not as a monomer.