CD244.1 Rat anti-Mouse, APC, Clone: C9.1, eBioscience™

Rat Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-2440-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg

Disclaimers: For Research Use Only.

Product Code. 15548066

Quantity Price
1 £ 182.82 / 100µg
Estimated Shipment date
from Supplier 07-06-2017
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Description and Specification


Antigen CD244.1
Applications Flow Cytometry
Clone C9.1
Concentration 0.2mg/mL
Conjugate Allophycocyanin
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias 2B4, SLAMF4, NK cell type I receptor protein
Host Species Rat
Isotype IgG2b
Quantity 100μg
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Target Species Murine

The monoclonal antibody C9.1 reacts with mouse CD244.1. This receptor is expressed on NK cells, gamma delta T cells, some CD8+ T cells, basophils, and monocytes on most inbred mouse strains except C57BL/6 and C58, which express the CD244.2 allotype. CD244 is a CD2-related receptor belonging to the SLAM family that exists as two different isoforms with opposing functions. CD244 associates with CD48, which is expressed widely on hematopoietic cells, regulates NK cell proliferation, cytotoxicity, and cytokine production. However, the CD244/CD28 interaction between NK and other cell types inhibits NK cytotoxicity, which contributes to self-tolerance. CD244 may enhance or inhibit CD8+ T cell effector function depending on SAP levels.

The C9.1 antibody has been reported to have antagonist activity on activated NK cells.