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CD243 (ABCB1) Mouse anti-Human, PE, Clone: UIC2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-2439-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15576946

  • £197.00 / 100 tests

EU Stock 1

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Description

Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
Specifications

Specifications

CD243 (ABCB1)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P08183
ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1, P-glycoprotein 1, colchicin sensitivity, doxorubicin resistance, multidrug resistance protein 1, CD243
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
UIC2
PE
ABCB1
Liquid
ABCB1
IgG2a, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
5243
Videos
Documents

For Research Use Only.