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CD243 (ABCB1) Mouse anti-Human, PE, Clone: UIC2, eBioscience™

Mouse Monoclonal Antibody

£85.50 - £197.00

Specifications

Antigen CD243 (ABCB1)
Clone UIC2
Target Species Human
Conjugate PE
Isotype IgG2a, kappa
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15566946
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Affymetrix eBioscience
12-2439-41
25 Tests £85.50
25 tests View alternative products
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Estimated Shipment
25-11-2020
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15576946
View Documents
Affymetrix eBioscience
12-2439-42
100 Tests £197.00
100 tests View alternative products
Save Up to 
»
Estimated Shipment
28-10-2020
Please to purchase this item. Need a web account? Register with us today!
Description

Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
Specifications

Specifications

CD243 (ABCB1)
Human
IgG2a, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
UIC2
PE
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.