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CD223 (LAG-3), eFluor 450, clone: eBioC9B7W (C9B7W), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 48-2231-82

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15351760

  • £121.00 / 100µg


EU Stock 2
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Description

Description

Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. eFluor® 450 is an alternative to Pacific Blue®. eFluor® 450 emits at 445 nm and is excited with the Violet laser (405 nm). Please make sure that your instrument is capable of detecting this fluorochome. Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser. Filtration: 0.2 μm post-manufacturing filtered. LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).
Specifications

Specifications

CD223 (Lag-3)
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q61790
CD223, LAG-3, Ly66
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
eBioC9B7W (C9B7W)
eFluor® 450
Lag3
Liquid
Lag3
IgG1, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
16768
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