CD223 (LAG-3) Rat anti-Mouse, eFluor® 450, Clone: eBioC9B7W (C9B7W), eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 48-2231-82
Code : Z2
Additional Details : Weight : 0.25000kg
DescriptionCell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. eFluor® 450 is an alternative to Pacific Blue®. eFluor® 450 emits at 445 nm and is excited with the Violet laser (405 nm). Please make sure that your instrument is capable of detecting this fluorochome. Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser. Filtration: 0.2 μm post-manufacturing filtered. LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|CD223, LAG-3, Ly66|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.