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CD223 (Lag-3) Mouse anti-Human, eFluor 450, Clone: 3DS223H, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 48-2239-42

UNSPSC : 41116133

Code : Z2

Additional Details : Weight : 194.64999kg

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Product Code. 15319965

  • £223.58 / Pack of 100


EU Stock 3
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Disclaimers:

For Research Use Only.


Specifications

Description

This 3DS223H monoclonal antibody recognizes human CD223 also known as Lymphocyte Activation Gene 3 (LAG-3). LAG-3 is a 70kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).

This 3DS223H antibody will recognize a formaldehyde-fixed epitope.
Description & Specifications

Specifications

CD223 (Lag-3)
3DS223H
eFluor 450
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.125μg)/test
Conjugated
Lymphocyte Activation Gene-3
IgG1
RUO
Primary
Human