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CD221 (IGF1R) Monoclonal Antibody (1H7), APC, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

£214.00

Specifications

Antigen CD221 (IGF1R)
Clone 1H7
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15568206
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Affymetrix eBioscience
17-8849-42
100 Tests
£214.00
100 tests
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Estimated Shipment: 07-05-2024
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Description

Description

Description: This 1H7 monoclonal antibody reacts with human insulin-like growth factor-1 receptor (IGF-1R), also known as CD221. This receptor is a cell surface-expressed glycoprotein composed of two extracellular alpha subunits and two transmembrane beta subunits that possess tyrosine kinase activity. Expressed on nearly all cell types, this receptor binds IGF-I and IGF-II, as well as insulin. Ligand binding leads to activation of the PI3K/Akt and MAPK pathways, which mediate cell proliferation and survival. Many tumors and transformed cells display altered IGF-1R expression. This monoclonal antibody has been reported to block binding of IGF-I and IGF-II to the IGF-1R. Applications Reported: This 1H7 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 1H7 antibody has been pre-titrated and tested by flow cytometric analysis of the HeLa cell line. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.

CD221 (IGF1R) Monoclonal antibody specifically detects CD221 (IGF1R) in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD221 (IGF1R)
5 μL/Test
Monoclonal
Liquid
RUO
P08069
IGF1R
Primary
4° C, store in dark, DO NOT FREEZE!
IGF1R
1H7
Flow Cytometry
APC
Mouse
Human
3480
IgG1 κ
Affinity chromatography
Antibody
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