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CD221 (IGF1R) Monoclonal Antibody (1H7), APC, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
£214.00
Specifications
Antigen | CD221 (IGF1R) |
---|---|
Clone | 1H7 |
Concentration | 5 μL/Test |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15568206
|
Affymetrix eBioscience
17-8849-42 |
100 Tests |
£214.00
100 tests |
Estimated Shipment: 07-05-2024 Log in to see stock. |
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Description
Description: This 1H7 monoclonal antibody reacts with human insulin-like growth factor-1 receptor (IGF-1R), also known as CD221. This receptor is a cell surface-expressed glycoprotein composed of two extracellular alpha subunits and two transmembrane beta subunits that possess tyrosine kinase activity. Expressed on nearly all cell types, this receptor binds IGF-I and IGF-II, as well as insulin. Ligand binding leads to activation of the PI3K/Akt and MAPK pathways, which mediate cell proliferation and survival. Many tumors and transformed cells display altered IGF-1R expression. This monoclonal antibody has been reported to block binding of IGF-I and IGF-II to the IGF-1R. Applications Reported: This 1H7 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 1H7 antibody has been pre-titrated and tested by flow cytometric analysis of the HeLa cell line. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.
CD221 (IGF1R) Monoclonal antibody specifically detects CD221 (IGF1R) in Human samples. It is validated for Flow Cytometry.Specifications
CD221 (IGF1R) | |
5 μL/Test | |
Monoclonal | |
Liquid | |
RUO | |
P08069 | |
IGF1R | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
IGF1R |
1H7 | |
Flow Cytometry | |
APC | |
Mouse | |
Human | |
3480 | |
IgG1 κ | |
Affinity chromatography | |
Antibody |
For Research Use Only.