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CD218a (IL-18Ra) Monoclonal Antibody (H44), PE, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
£105.00 - £237.00
Specifications
Antigen | CD218a (IL-18Ra) |
---|---|
Clone | H44 |
Concentration | 5 μL/Test |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15557106
|
Affymetrix eBioscience
12-7183-42 |
100 Tests |
£237.00
100 tests |
Estimated Shipment: 07-05-2024 Log in to see stock. |
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15547106
|
Affymetrix eBioscience
12-7183-41 |
25 Tests |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
Description: The H44 antibody reacts with the interleukin-18 receptor alpha chain, also known as IL-1Rrp, an IL-1R family member. IL-18R alpha is expressed on Th1 cells, NK cell subset, neutrophils and IL-12-stimulated tonsillar B cells. By itself, IL-18R alpha binds IL-18 with low affinity and when complexed with IL-18R beta chain binds IL-18 with high affinity. The proinflammatory cytokine IL-18 and its receptor complex play an important role in the innate and autoimmune responses. Applications Reported: H44 has been reported for use in flow cytometric analysis. Applications Tested: This H44 antibody has been pre-titrated and tested by flow cytometric analysis on human peripheral blood cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended to stain whole blood before RBC lysis. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.
IL18R1 is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. The gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q.Specifications
CD218a (IL-18Ra) | |
5 μL/Test | |
Monoclonal | |
Liquid | |
RUO | |
Q13478 | |
IgG1 κ | |
Affinity chromatography | |
Antibody |
H44 | |
Flow Cytometry | |
PE | |
Mouse | |
Human | |
8809 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! |
For Research Use Only.